Organic Chemistry
Consulting Services

// Small Molecule Design & Synthesis Expertise

Professional organic chemistry consulting with 10+ years of experience in medicinal chemistry, custom synthesis, and pharmaceutical route optimization. From concept to commercialization.

Start Project View Portfolio

Expert Services

// Comprehensive Organic Chemistry Solutions

Custom Synthesis

Design and execute complex multi-step syntheses for pharmaceutical intermediates, natural products, and specialty chemicals. Expert in asymmetric synthesis and stereochemistry control.

Route Optimization

Streamline existing synthetic pathways to reduce steps, improve yields, and minimize costs. Process chemistry expertise for scale-up and manufacturing optimization.

Molecular Design

Structure-activity relationship analysis and molecular design for drug discovery. Computational chemistry support and retrosynthetic analysis for complex targets.

Literature Research

Comprehensive patent and literature searches. Competitive intelligence and freedom-to-operate analysis. Technical due diligence for pharmaceutical investments.

Process Development

Scale-up chemistry from laboratory to manufacturing. Process safety evaluation, impurity profiling, and regulatory submission support for pharmaceutical processes.

Training & Education

Technical training for R&D teams. Workshops on modern synthetic methods, reaction mechanisms, and problem-solving strategies in organic chemistry.

About Dr. Chen Wei

// Organic Chemistry PhD with Industrial Experience

Dr. Chen Wei
PhD in Organic Chemistry - Peking University (2012)
Senior Scientist - Novartis (2012-2018)
Lead Chemist - BeiGene (2018-2022)
20+ Publications in J. Am. Chem. Soc., Angew. Chem.
15+ Patents in Pharmaceutical Chemistry
Consultant for 50+ Biotech Companies
English, Chinese, German Fluent

Selected Projects

// Case Studies & Success Stories

Molecular Structure
Coming Soon

API Synthesis Optimization

Redesigned a 12-step synthesis route for a cardiovascular drug API, reducing to 6 steps with 45% overall yield improvement and 60% cost reduction. Key improvements included telescoped reactions and elimination of chromatographic purifications.

Process Chemistry Scale-up Cost Reduction
Natural Product
Structure

Natural Product Total Synthesis

First asymmetric total synthesis of a marine alkaloid with potent anti-cancer activity. 15-step route featuring innovative cascade cyclization reaction and excellent stereochemical control throughout the sequence.

Total Synthesis Stereochemistry Method Development
Compound Library
Preview

Pharmaceutical Intermediate Library

Designed and synthesized a focused library of 200+ heterocyclic compounds for a kinase inhibitor program, leading to 3 clinical candidates. Structure-activity relationships guided optimization strategy.

Med Chem SAR Drug Discovery
Green Chemistry
Route

Green Chemistry Implementation

Developed environmentally friendly synthesis route replacing toxic reagents and reducing waste by 80% for a diabetes treatment manufacturing process. Achieved same efficiency with safer reagents.

Green Chemistry Sustainability Manufacturing
Chiral Auxiliary
Design

Chiral Auxiliary Development

Designed novel chiral auxiliary for enantioselective synthesis of β-amino acids, achieving >95% ee with broad substrate scope and easy recovery. Patent application filed for this innovative methodology.

Asymmetric Synthesis Methodology Chirality
Alternative
Synthesis Route

Patent Circumvention Strategy

Developed alternative synthetic routes for blockbuster drug to avoid patent restrictions while maintaining cost-effectiveness for generic manufacturing. Successfully passed regulatory review.

Patent Analysis Generic Drugs IP Strategy

Let's Collaborate

// Ready to Start Your Next Project?

Email

[oriwoodwild@gmail.com]